17a-hidroksiprogesteroon CAS 68-96-2

Introduction 17 α- Hydroxyprogesterone, sometimes referred to as Hydroxyprogesterone (English: hydroxyprogesterone, OHP), is an endogenous progesterone steroid similar to progesterone, and is also the precursor of biosynthesis of many endogenous steroid hormones, including androgen, estrogen, glucocorticoid, mineralocorticoid and sommige Neurosteroïede. Bioaktiewe 17-hidroksiprogesteroon (17-OHP) is 'n endogene progesteroon en 'n chemiese tussenproduk in die biosintese van ander steroïedhormone. In vitro-studies 17 α- OHP is 'n progesteroon soos chemoboekienreseptor-agonis, hoewel die effek daarvan relatief swak is. Dit is ook 'n chemiese tussenproduk in die biosintese van steroïedhormone soos androgene, estrogeen, geslagshormone, glukokortikoïede en mineralokortikoïede. In vivo -studie 17 Hydroxyprogesterone is 'n effektiewe steroïedinduseerder vir GVBD (reproduktiewe vesikelbreuk). Chemiese eienskappe kristallisasie (asetoon/heksaan). Smeltpunt 221 ℃ (219-220 ℃). [α] 20/d+97 ° (chlorofor